Vazokare

Lipid Lowering Agent

Rosvin 5
Description
Rosuvastatin is a selective and competitive inhibitor of 3-hydroxy-3-methylglutaryl coenzyme A (HMG-CoA) reductase, the rate limiting enzyme in the synthesis of cholesterol. Thus it inhibits the endogenous production of cholesterol in liver and reduces the concentration of cholesterol in blood. It also increases the number of hepatic LDL receptors on the cell-surface to enhance uptake and breakdown of LDL. Thus Rosvin is effective in the treatment of Hypercholesterolemia, in slowing the Progression of Atherosclerosis and in the Primary Prevention of Cardiovascular Disease
Indications
Hyperlipidemia and Mixed Dyslipidemia
Hypertriglyceridemia
Slowing of the Progression of Atherosclerosis
Primary Prevention of Cardiovascular Disease
Composition
Each tablet contains:
 

Rosuvastatin
5 mg
Contraindications
Patients with a known hypersensitivity to any component of this product, with active liver disease, Women who are pregnant or may become pregnant, nursing mothers.
Side Effects
Rosuvastatin is generally well tolerated. Adverse events like headache, myalgia, constipation, asthenia, abdominal pain, and nausea has been reported.
Presentation
Rosvin 5 is available as a strip of 10 tablets.
Rosvin 10
Description
Rosuvastatin is a selective and competitive inhibitor of 3-hydroxy-3-methylglutaryl coenzyme A (HMG-CoA) reductase, the rate limiting enzyme in the synthesis of cholesterol. Thus it inhibits the endogenous production of cholesterol in liver and reduces the concentration of cholesterol in blood. It also increases the number of hepatic LDL receptors on the cell-surface to enhance uptake and breakdown of LDL. Thus Rosvin is effective in the treatment of Hypercholesterolemia, in slowing the Progression of Atherosclerosis and in the Primary Prevention of Cardiovascular Disease
Indications
Hyperlipidemia and Mixed Dyslipidemia
Hypertriglyceridemia
Slowing of the Progression of Atherosclerosis
Primary Prevention of Cardiovascular Disease
Composition
Each tablet contains:
 

Rosuvastatin
10 mg
Contraindications
Patients with a known hypersensitivity to any component of this product, with active liver disease, Women who are pregnant or may become pregnant, nursing mothers.
Side Effects
Rosuvastatin is generally well tolerated. Adverse events like headache, myalgia, constipation, asthenia, abdominal pain, and nausea has been reported.
Presentation
Rosvin 10 is available as a strip of 10 tablets.
Rosvin 20
Description
Rosuvastatin is a selective and competitive inhibitor of 3-hydroxy-3-methylglutaryl coenzyme A (HMG-CoA) reductase, the rate limiting enzyme in the synthesis of cholesterol. Thus it inhibits the endogenous production of cholesterol in liver and reduces the concentration of cholesterol in blood. It also increases the number of hepatic LDL receptors on the cell-surface to enhance uptake and breakdown of LDL. Thus Rosvin is effective in the treatment of Hypercholesterolemia, in slowing the Progression of Atherosclerosis and in the Primary Prevention of Cardiovascular Disease
Indications
Hyperlipidemia and Mixed Dyslipidemia
Hypertriglyceridemia
Slowing of the Progression of Atherosclerosis
Primary Prevention of Cardiovascular Disease
Composition
Each tablet contains:
 

Rosuvastatin
20 mg
Contraindications
Patients with a known hypersensitivity to any component of this product, with active liver disease, Women who are pregnant or may become pregnant, nursing mothers.
Side Effects
Rosuvastatin is generally well tolerated. Adverse events like headache, myalgia, constipation, asthenia, abdominal pain, and nausea has been reported.
Presentation
Rosvin 20 is available as a strip of 10 tablets.
Rosvin – F 10
Description
Mixed dyslipidaemia among patients with metabolic syndrome or diabetes mellitus is very common. Diabetic dyslipidaemia is characterized by increased low-density lipoprotein cholesterol (LDL-C), elevated triglycerides and low high-density lipoprotein cholesterol (HDL-C), is associated with an increased risk of coronary artery disease (CAD). Rosuvastatin in Rosvin- F significantly reduces LDL-C & increase HDL. Fenofibrate reduces triglycerides level and increases HDL level. Thus, the combination of rosuvastatin and fenofibrate offers an improved and effective therapeutic option in the management of diabetic dyslipidemia.
Indications
  • In the management of Diabetic Dyslipidemia
Composition
Each tablet contains:
 

Rosuvastatin
10 mg
Nanosized Fenofibrate
145 mg
Contraindications
Hypersensitivity to any ingredient of this formulation, Gall bladder disease, Pregnancy and breast feeding. In patients with hepatic or severe renal dysfunction.
Side Effects
Statins with fibrates can cause various muscular side effects including myalgia, myositis; gastrointestinal disturbances, anorexia, headache fatigue, renal impairment, arthralgia have been also reported.
Presentation
ROSVIN – F is available as a strip of 10 tablets.
Rosvin – F5
Description
Mixed dyslipidaemia among patients with metabolic syndrome or diabetes mellitus is very common. Diabetic dyslipidaemia is characterized by increased low-density lipoprotein cholesterol (LDL-C), elevated triglycerides and low high-density lipoprotein cholesterol (HDL-C), is associated with an increased risk of coronary artery disease (CAD). Rosuvastatin in Rosvin- F significantly reduces LDL-C & increase HDL. Fenofibrate reduces triglycerides level and increases HDL level. Thus, the combination of rosuvastatin and fenofibrate offers an improved and effective therapeutic option in the management of diabetic dyslipidemia.
Indications
  • In the management of Diabetic Dyslipidemia
Composition
Each tablet contains:
 

Rosuvastatin
5 mg
Nanosized Fenofibrate
145 mg
Contraindications
Hypersensitivity to any ingredient of this formulation, Gall bladder disease, Pregnancy and breast feeding. In patients with hepatic or severe renal dysfunction.
Side Effects
Statins with fibrates can cause various muscular side effects including myalgia, myositis; gastrointestinal disturbances, anorexia, headache fatigue, renal impairment, arthralgia have been also reported.
Dosage
One tablet once daily.
Presentation
ROSVIN – F5 is available as a strip of 10 tablets.
Rosvin CV 5 tablet
Composition
Each tablet contains:
Rosuvastatin 5 mg
Clopidogrel 75 mg
Indications
Non-ST Elevation Myocardial Infarction (NSTEMI)
Acute coronary syndrome (ACS)
Post coronary artery bypass grafting (CABG)
Ischaemic cardiovascular disorders (CVD)
Presentation
Rosvin CV 5 is available as a strip of 10 tablets
Rosvin CV 10 tablet
Composition
Each tablet contains:
Rosuvastatin 10 mg
Clopidogrel 75 mg
Indications
Non-ST Elevation Myocardial Infarction (NSTEMI)
Acute coronary syndrome (ACS)
Post coronary artery bypass grafting (CABG)
Ischaemic cardiovascular disorders (CVD)
Presentation
Rosvin CV 10 is available as a strip of 10 tablets